Nanos Homolog 1 antibody (C-Term)

Catalog No. ABIN374534

The Goat Polyclonal anti-Nanos Homolog 1 antibody is suitable to detect Nanos Homolog 1 in samples from Human. It has been validated for WB.

Quick Overview for Nanos Homolog 1 antibody (C-Term) (ABIN374534)

Target: Nanos Homolog 1 (NANOS1)

Reactivity: Human

Host: Goat

Clonality: Polyclonal

Conjugate: This Nanos Homolog 1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-Nanos Homolog 1 Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to NANOS1.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-SARDGPPGKKLR, from the C Terminus of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/64000. Western Blot: 1 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Nanos Homolog 1

Target: Nanos Homolog 1 (NANOS1)

Alternative Name: NANOS1

Background: NANOS1 may regulate the translation of specific mRNAs by forming a complex with PUM2 that associates with the 3' untranslated regions (UTRs) of mRNA targets. Predominantly expressed in testis. Specifically expressed during germline development. In adult tissues, it is mainly expressed in spermatogonia, the stem cells of the germline. Also expressed during meiosis in spermatocytes. Not present in late, post-meiotic stage germ cells. Expressed in fetal ovaries, while it is weakly or not expressed in mature postmeiotic oocytes, suggesting that it may be expressed in premeiotic female germ cells.Synonyms: NOS1, Nanos homolog 1

Gene ID: 340719, 9606

UniProt: Q8WY41

Pathways: Negative Regulation of Hormone Secretion, Myometrial Relaxation and Contraction