CBX1 antibody (Internal Region)

Catalog No. ABIN374618

The Goat Polyclonal anti-CBX1 antibody is suitable to detect CBX1 in samples from Human, Mouse, Rat and Dog. It has been validated for WB and IHC (p).

Quick Overview for CBX1 antibody (Internal Region) (ABIN374618)

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Reactivity: Human, Mouse, Rat, Dog

Host: Goat

Clonality: Polyclonal

Conjugate: This CBX1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-CBX1 Antibody

Binding Specificity: Internal Region

Specificity: This antibody reacts to Chromobox protein homolog 1.

Cross-Reactivity (Details): Species reactivity (expected):Mouse, Rat, Canine, Bovine.
Species reactivity (tested):Human.

Purification: Affinity chromatography

Immunogen: Peptide with sequence C-QSQKTAHETDKSE, from the internal region of the protein sequence

Application Details

Application Notes: Peptide ELISA: 1/32000. Western Blot: 0.3 - 1.0 μg/mL. Immunohistochemistry on paraffin sections: 2 - 3 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 0,5 mg/mL

Buffer: Tris saline, 0.02 % sodium azide, pH 7.3 with 0.5 % bovine serum albumin

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for CBX1

Target: CBX1 (Chromobox Homolog 1 (CBX1))

Alternative Name: CBX1

Background: Heterochromatin protein-1 (HP1) is localized at heterochromatin sites, where it mediates gene silencing.A component of heterochromatin HP1 recognizes and binds histone H3, leading to epigenetic repression. HP1 may interact with lamin B receptor (LBR), this interaction can contribute to the association of the heterochromatin with the inner nuclear membrane.Synonyms: Chromobox protein homolog 1, HP1 beta, HP1-beta, HP1Hsbeta, Heterochromatin protein 1 homolog beta, Heterochromatin protein p25, M31, Modifier 1 protein, p25beta

Gene ID: 10951, 9606

UniProt: P83916