ITGA4 antibody (PE)

Catalog No. ABIN375522

This anti-ITGA4 antibody is a Rat Monoclonal antibody detecting ITGA4 in FACS. Suitable for Mouse.

Quick Overview for ITGA4 antibody (PE) (ABIN375522)

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This ITGA4 antibody is conjugated to PE

Application: Flow Cytometry (FACS)

Clone: DATK32

Product Details anti-ITGA4 Antibody (PE)

Specificity: Mouse LPAM-1

Characteristics: Rat Anti-Mouse LPAM-1-PE

Purification: Purified

Immunogen: AKR/Cum mouse T lymphoma cell line TK-1

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , Block - Reported in literature , IP - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells BIOT conjugate 1 g/106 cells PE conjugate 0.1 g/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Comment:

Blockade of binding to cell adhesion molecules, Induction of homotypic cellular aggregation

Sample Volume: 2 mL

Restrictions: For Research Use only

Handling

Concentration: 0.1 mg/mL

Buffer: 0.1 mg in 1.0 mL or 0.2 mg in 2.0 mL of PBS/Sodium azide and a stabilizing agent

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for ITGA4

Target: ITGA4 (Integrin alpha 4 (ITGA4))

Background: The lymphocyte Peyer's patch adhesion molecule (LPAM-1), also known as integrin α 4 β 7, is a member of the integrin family of cell surface receptors. It is expressed primarily on mucosal lymphocytes, but is also present on NK cells and eosinophils. The α 4 β 7 heterodimer mediates the binding of lymphocytes to its ligand, mucosal vascular addressin (MAdCAM-1) on the high endothelial venules, thereby directing the homing of lymphocytes into Peyer's patches and intestinal lamina propria.

Pathways: Integrin Complex