CD14 antibody (APC-Cy7)

Catalog No. ABIN375867

This anti-CD14 antibody is a Mouse Monoclonal antibody detecting CD14 in FACS. Suitable for Human.

Quick Overview for CD14 antibody (APC-Cy7) (ABIN375867)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to APC-Cy7

Application: Flow Cytometry (FACS)

Clone: 61D3

Product Details anti-CD14 Antibody (APC-Cy7)

Specificity: Human/Cynomolgus/Canine/Hooded Seal CD14, Mr 55 kDa

Characteristics: Mouse Anti-Human CD14-APC/CY7

Purification: Purified

Immunogen: Human peripheral monocytes

Isotype: IgG1

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , WB - Reported in literature , ELISA - Reported in literature , Cyto - Reported in literature , Block - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, APC, SPRD, PE/CY5.5, PE/CY7, APC/CY5.5, 10 L/106 cells APC/CY7, AF488, AF647, and AF700 conjugates For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Restrictions: For Research Use only

Handling

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze!
Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD14 is a 53-55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades