CD14 antibody (Biotin)

Catalog No. ABIN376018

This Mouse Monoclonal antibody specifically detects CD14 in FACS. It exhibits reactivity toward Human.

Quick Overview for CD14 antibody (Biotin) (ABIN376018)

Target: CD14

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is conjugated to Biotin

Application: Flow Cytometry (FACS)

Clone: UCHM-1

Product Details anti-CD14 Antibody (Biotin)

Specificity: Human/Cynomolgus CD14, Mr 55 kDa

Characteristics: Mouse Anti-Human CD14-BIOT

Purification: Purified

Immunogen: Thymocytes and peripheral blood lymphocytes from a remission AML patient

Isotype: IgG2a

Application Details

Application Notes:

• Applications: FC - Quality tested , IHC-FS - Reported in literature , ICC - Reported in literature , IP - Reported in literature , ELISA - Reported in literature , Block - Reported in literature , Depletion - Reported in literature
• Working Dilutions: Flow Cytometry Purified (UNLB) antibody 1 g/106 cells FITC, BIOT, PE, and SPRD conjugates 10 L/106 cells For flow cytometry, the suggested use of these reagents is in a final volume of 100 L

Restrictions: For Research Use only

Handling

Buffer: 100 tests in 1.0 mL of PBS/Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Protect conjugated products from light.
Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: Store at 2-8°C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD14 is a 53-55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades