CD79b antibody

Catalog No. ABIN376383

The Hamster Monoclonal anti-CD79b antibody (Clone HM79-12) (ABIN376383) specifically detects CD79b in WB, FACS and IP. The antibody is reactive with Mouse samples.

Quick Overview for CD79b antibody (ABIN376383)

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Reactivity: Mouse

Host: Hamster

Clonality: Monoclonal

Conjugate: This CD79b antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunoprecipitation (IP)

Clone: HM79-12

Product Details anti-CD79b Antibody

Purpose: Hamster Anti-Mouse CD79b-LE/AF

Specificity: Mouse CD79b, Mr 37-39 kDa

Characteristics: Low Endotoxin/Azide Free Anti-Mouse CD79b antibody for use in flow cytometry, western blotting, and immunoprecipitation assays.

Endotoxin Level: Low Endotoxin

Immunogen: CD79alpha/CD79beta heterodimers purified from mouse (BALB/c x NZB)F1 B cell lymphoma cells, WEHI231

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD79b

Target: CD79b (CD79B) (CD79b Molecule, Immunoglobulin-Associated beta (CD79B))

Alternative Name: CD79b

Background: Murine CD79 is a 23/21 kDa disulfide-linked heterodimer composed of an α chain (CD79a/mb-1) and a β chain (CD79b/B29) that associates non-covalently with membrane immunoglobulin (Ig) to form the B cell receptor (BCR) complex. Its expression is restricted to B lymphocytes, first appearing on the surface at the pro-B cell stage prior to productive Ig gene rearrangements and remaining through all stages of B-cell differentiation prior to plasma cells. It has been proposed that the CD79 complex on pro-B cell surfaces may function to induce early B-cell differentiation.

Gene ID: 15985

UniProt: P15530

Pathways: BCR Signaling