CD14 antibody

Catalog No. ABIN376396

This Mouse Monoclonal antibody specifically detects CD14 in FACS, WB, ELISA, ICC, IHC (fro), BR, Sep and CyTox. It exhibits reactivity toward Human, Cynomolgus, Dog and Cystophora cristata (Hooded seal).

Quick Overview for CD14 antibody (ABIN376396)

Target: CD14

Reactivity: Human, Cynomolgus, Dog, Cystophora cristata (Hooded seal)

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD14 antibody is un-conjugated

Application: Flow Cytometry (FACS), Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Blocking Reagent (BR), Separation (Sep), Cytotoxicity Test (CyTox)

Clone: 61D3

Product Details anti-CD14 Antibody

Purpose: Mouse Anti-Human CD14-LE/AF

Characteristics: Low Endotoxin/Azide Free Anti-Human CD14 antibody for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, ELISA, cytotoxicity, blocking, and separation assays.

Endotoxin Level: Low Endotoxin

Immunogen: Human peripheral monocytes

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: Phosphate buffered saline, pH 7.4

Preservative: Azide free

Handling Advice: Each reagent is stable for the period shown on the bottle label if stored as directed.

Storage: 4 °C

Storage Comment: 2-8°C

Target Details for CD14

Target: CD14

Alternative Name: CD14

Background: CD14 is a 53-55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.

Gene ID: 929, 102129342

UniProt: P08571

Pathways: TLR Signaling, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Toll-Like Receptors Cascades