APP antibody (AA 400-450)

Catalog No. ABIN377319

This anti-APP antibody is a Rabbit Polyclonal antibody detecting APP in WB and IHC. Suitable for Human, Mouse and Rat.

Quick Overview for APP antibody (AA 400-450) (ABIN377319)

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APP antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Product Details anti-APP Antibody

Binding Specificity: AA 400-450

Specificity: Specific for APP.

Purification: Purified

Immunogen: Synthetic peptide from human Amyloid beta A4 protein (Alzheimer disease amyloid A4 protein homolog, ABPP, APP) conjugated to an immunogenic carrier protein. The immunogen is homologous in many species including rat, mouse, monkey, zebra fish, chicken and xenopus.

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: IHC, WB

Usage: IHC: Antigen retrieval is essential for use on paraffin sections.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Sterile water

Concentration: Lot specific

Buffer: Lyophilized. Centrifuge to remove any insoluble material

Handling Advice: Avoid freeze and thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Maintain lyophilized and reconstituted antibodies at -20°C for long term storage and at 2-8°C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze/thaw cycles.

Target Details for APP

Target: APP (Amyloid beta (A4) Precursor Protein (APP))

Alternative Name: APP / beta Amyloid

Background: Name/Gene ID: APP
Family: Amyloid precursor protein

Synonyms: APP, ABPP, A4, ABETA, AD1, Alzheimer disease, Amyloid beta, Beta-amyloid peptide, APPI, Beta amyloid, CVAP, AAA, PN2, PreA4, Amyloid beta A4 protein, Peptidase nexin-II, CTFgamma, PN-II, Protease nexin-II

Gene ID: 351

UniProt: P05067

Pathways: Caspase Cascade in Apoptosis, EGFR Signaling Pathway, Transition Metal Ion Homeostasis, Skeletal Muscle Fiber Development, Toll-Like Receptors Cascades, Feeding Behaviour