CDC25A antibody

Catalog No. ABIN379102

The Mouse Monoclonal anti-CDC25A antibody (Clone DCS-120-DCS-121) (ABIN379102) specifically detects CDC25A in WB, IHC and IP. The antibody is reactive with Human and Rat samples.

Quick Overview for CDC25A antibody (ABIN379102)

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Reactivity: Human, Rat

Host: Mouse

Clonality: Monoclonal

Conjugate: This CDC25A antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Clone: DCS-120-DCS-121

Product Details anti-CDC25A Antibody

Specificity: Reacts with a 65 kD protein known as CDC25A. The activity of cyclin-dependent kinases in cell cycle is regulated by the phosphorylation status, which is controlled by the antagonistic action of wee 1 kinase and CDC25 phosphatases. Three CDC25 genes are present in human cells: CDC25A, CDC25B and CDC25C. CDC25A and CDC25B are expressed throughout the cell cycle, with peak expression in G1 for CDC25A and in both G1-S phase and G2 for CDC25B. CDC25C is mainly expressed in G2 phase. This antibody cross reacts with rat.

Purification: Ig fraction

Immunogen: BALB/C mice were injected with purified recombinant CDC25A.

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Buffer contains: 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Do not freeze.

Storage: 4 °C

Storage Comment: Store at 2-8°C. Do not freeze.

Target Details for CDC25A

Target: CDC25A (Cell Division Cycle 25 Homolog A (S. Pombe) (CDC25A))

Alternative Name: CDC25A

Background: Name/Gene ID: CDC25A
Subfamily: CDC25
Family: Protein Phosphatase

Synonyms: CDC25A, CDC25A2-CAG isoform, Cell division cycle 25A, CDC25A phosphatase, CDC25Hu1, M-phase inducer phosphatase 1, CDC25A2

Gene ID: 993

UniProt: P30304

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases, M Phase