PRMT3 antibody (N-Term)

Catalog No. ABIN387838

This Rabbit Polyclonal antibody specifically detects PRMT3 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for PRMT3 antibody (N-Term) (ABIN387838)

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PRMT3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB0029

Product Details anti-PRMT3 Antibody

Binding Specificity: AA 142-173, N-Term

Predicted Reactivity: M

Purification: This antibody is purified through a protein G column, followed by dialysis against PBS.

Immunogen: This PRMT3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 142-173 amino acids from the N-terminal region of human PRMT3.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:2000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified monoclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PRMT3

Target: PRMT3 (Protein Arginine Methyltransferase 3 (PRMT3))

Alternative Name: PRMT3

Background: Arginine methylation is an irreversible post translational modification which has only recently been linked to protein activity. At least three types of PRMT enzymes have been identified in mammalian cells. These enzymes have been shown to have essential regulatory functions by methylation of key proteins in several fundamental areas. These protein include nuclear proteins, IL enhancer binding factor, nuclear factors, cell cycle proteins, signal transduction proteins, apoptosis proteins, and viral proteins. The mammalian PRMT family currently consists of 7 members that share two large domains of homology. Outside of these domains, epitopes were identified and antibodies against all 7 PRMT members have been developed.

Molecular Weight: 59903

Gene ID: 10196

NCBI Accession: NP_005779

UniProt: O60678

Pathways: Protein targeting to Nucleus