IDO1 antibody (C-Term)

Catalog No. ABIN389194

This Rabbit Polyclonal antibody specifically detects IDO1 in WB and IHC (p). It exhibits reactivity toward Humanand has been mentioned in 1 publication.

Quick Overview for IDO1 antibody (C-Term) (ABIN389194)

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IDO1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB15061

Product Details anti-IDO1 Antibody

Binding Specificity: AA 374-403, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This INDO antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 374-403 amino acids from the C-terminal region of human INDO.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-IDO1 antibody (ABIN389194)

Ishiguro, Watanabe, Nakamura, Yamamura, Ando, Goto, Hirooka: "S100G expression and function in fibroblasts on colitis induction." in: International immunopharmacology, Vol. 39, pp. 92-96, (2017) (PubMed).

Target Details for IDO1

Target: IDO1 (Indoleamine 2,3-Dioxygenase 1 (IDO1))

Alternative Name: INDO

Background: Gamma-interferon (IFNG, MIM 147570) has an antiproliferative effect on many tumor cells and inhibits intracellular pathogens such as Toxoplasma and Chlamydia, at least partly because of the induction of indoleamine 2,3-dioxygenase (INDO, EC 1.13.11.52). This enzyme catalyzes the degradation of the essential amino acid L-tryptophan to N-formyl-kynurenine.[supplied by OMIM]

Molecular Weight: 45326

Gene ID: 3620

NCBI Accession: NP_002155

UniProt: P14902

Pathways: Activated T Cell Proliferation