beta-2 Microglobulin antibody (C-Term)

Catalog No. ABIN389259

Cited in 1 publication. The Rabbit Polyclonal anti-beta-2 Microglobulin antibody (Clone RB14613) (ABIN389259) specifically detects beta-2 Microglobulin in WB, FACS and IHC (p). The antibody is reactive with Human samples.

Quick Overview for beta-2 Microglobulin antibody (C-Term) (ABIN389259)

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This beta-2 Microglobulin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14613

Product Details anti-beta-2 Microglobulin Antibody

Binding Specificity: AA 86-118, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This B2M antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-118 amino acids from the C-terminal region of human B2M.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-beta-2 Microglobulin antibody (ABIN389259)

Liu, Yang, Li, Liu, Miao, Yang, Zou, Yuan: "Overexpression of B2M and loss of ALK7 expression are associated with invasion, metastasis, and poor-prognosis of the pancreatic ductal adenocarcinoma." in: Cancer biomarkers : section A of Disease markers, Vol. 15, Issue 6, pp. 735-43, (2015) (PubMed).

Target Details for beta-2 Microglobulin

Target: beta-2 Microglobulin (B2M) (beta-2-Microglobulin (B2M))

Alternative Name: B2M

Background: Beta-2-microglobulin is a serum protein found in association with the major histocompatibility complex (MHC) class I heavy chain on the surface of nearly all nucleated cells.

Molecular Weight: 13715

Gene ID: 567

NCBI Accession: NP_004039

UniProt: P61769

Pathways: TCR Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process