HNF4A antibody (AA 118-146)

Catalog No. ABIN389268

The Rabbit Polyclonal anti-HNF4A antibody (Clone RB16247) (ABIN389268) specifically detects HNF4A in WB. The antibody is reactive with Human samples.

Quick Overview for HNF4A antibody (AA 118-146) (ABIN389268)

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HNF4A antibody is un-conjugated

Application: Western Blotting (WB)

Clone: RB16247

Product Details anti-HNF4A Antibody

Binding Specificity: AA 118-146

Predicted Reactivity: M, Rat, X

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This HNF4A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 118-146 amino acids from human HNF4A.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for HNF4A

Target: HNF4A (Hepatocyte Nuclear Factor 4, alpha (HNF4A))

Alternative Name: HNF4A

Background: HNF4A is a nuclear transcription factor which binds DNA as a homodimer. This protein controls the expression of several genes, including hepatocyte nuclear factor 1 alpha, a transcription factor which regulates the expression of several hepatic genes. This protein may play a role in development of the liver, kidney, and intestines. Mutations in this protein have been associated with monogenic autosomal dominant non-insulin-dependent diabetes mellitus type I.

Molecular Weight: 52785

Gene ID: 3172

NCBI Accession: NP_000448, NP_001025174, NP_001025175, NP_001245284, NP_787110, NP_849181

UniProt: P41235

Pathways: AMPK Signaling, Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Carbohydrate Homeostasis, Cell-Cell Junction Organization, Regulation of Carbohydrate Metabolic Process