ENO2/NSE antibody (pTyr236)

Catalog No. ABIN389972

There are 2+ publications for this product available. The Rabbit Polyclonal anti-ENO2/NSE antibody is suitable to detect ENO2/NSE in samples from Human. It has been validated for DB.

Quick Overview for ENO2/NSE antibody (pTyr236) (ABIN389972)

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ENO2/NSE antibody is un-conjugated

Application: Dot Blot (DB)

Clone: RB16241

Product Details anti-ENO2/NSE Antibody

Binding Specificity: pTyr236

Predicted Reactivity: M, Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This NSE Antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding Y236 of human NSE.

Isotype: Ig Fraction

Application Details

Application Notes: DB: 1:500

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

References for anti-ENO2/NSE antibody (ABIN389972)

Hares, Redondo, Kemp, Rice, Scolding, Wilkins: "Axonal motor protein KIF5A and associated cargo deficits in multiple sclerosis lesional and normal-appearing white matter." in: Neuropathology and applied neurobiology, Vol. 43, Issue 3, pp. 227-241, (2018) (PubMed).

Hares, Kemp, Rice, Gray, Scolding, Wilkins: "Reduced axonal motor protein expression in non-lesional grey matter in multiple sclerosis." in: Multiple sclerosis (Houndmills, Basingstoke, England), (2013) (PubMed).

Target Details for ENO2/NSE

Target: ENO2/NSE (ENO2) (Enolase 2 (Gamma, Neuronal) (ENO2))

Alternative Name: NSE

Background: NSE is one of the three enolase isoenzymes found in mammals. This isoenzyme, a homodimer, is found in mature neurons and cells of neuronal origin. A switch from alpha enolase to gamma enolase occurs in neural tissue during development in rats and primates.

Molecular Weight: 47269

Gene ID: 2026

NCBI Accession: NP_001966

UniProt: P09104