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Aurora Kinase C antibody (AA 115-145)

AURKC Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB6822 unconjugated
Catalog No. ABIN390979
  • Target See all Aurora Kinase C (AURKC) Antibodies
    Aurora Kinase C (AURKC)
    Binding Specificity
    • 19
    • 9
    • 8
    • 6
    • 6
    • 5
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 115-145
    Reactivity
    • 68
    • 21
    • 17
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 67
    • 2
    • 1
    Rabbit
    Clonality
    • 70
    Polyclonal
    Conjugate
    • 32
    • 7
    • 6
    • 6
    • 4
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Aurora Kinase C antibody is un-conjugated
    Application
    • 63
    • 41
    • 28
    • 13
    • 9
    • 3
    • 1
    Western Blotting (WB)
    Purification
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This Aurora-C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 115-145 amino acids from the Central region of human Aurora-C.
    Clone
    RB6822
    Isotype
    Ig Fraction
    Top Product
    Discover our top product AURKC Primary Antibody
  • Application Notes
    WB: 1:1000. WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Burum-Auensen, Skotheim, Schjølberg, Røislien, Lothe, Clausen: "Spindle proteins are differentially expressed in the various histological subtypes of testicular germ cell tumors." in: Journal of carcinogenesis, Vol. 9, pp. 1, (2010) (PubMed).

  • Target
    Aurora Kinase C (AURKC)
    Alternative Name
    Aurora-C (AURKC Products)
    Synonyms
    AURKC antibody, AIE2 antibody, AIK3 antibody, ARK3 antibody, AurC antibody, SPGF5 antibody, STK13 antibody, aurora-C antibody, AIE1 antibody, ARK-3 antibody, IAK3 antibody, Stk13 antibody, aurora kinase C antibody, AURKC antibody, Aurkc antibody
    Background
    Chromosomal segregation during mitosis as well as meiosis is regulated by kinases and phosphatases. The Aurora kinases, members of the Ser/Thr protein kinase family, associate with microtubules during chromosome movement and segregation. Aurora kinase C may play a part in organizing microtubules in relation to the function of the centrosome/spindle pole during mitosis. This protein is localized to centrosome from anaphase to cytokinesis. Expression is limited to testis in normal cells. Elevated expression levels are seen only in a subset of cancer cells such as HepG2, HuH7 and HeLa cells. Aurora-C expression is maximum at M phase.
    Molecular Weight
    35591
    Gene ID
    6795
    NCBI Accession
    NP_001015878, NP_001015879, NP_003151
    UniProt
    Q9UQB9
    Pathways
    Cell Division Cycle, Maintenance of Protein Location
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