PLK2 antibody (C-Term)

Catalog No. ABIN391375

Product Details anti-PLK2 Antibody

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Binding Specificity: AA 375-406, C-Term

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PLK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This PLK2 (SNK) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 375-406 amino acids from the C-terminal region of human PLK2 (SNK).

Clone: RB0873

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PLK2

Target: PLK2 (Polo-Like Kinase 2 (PLK2))

Alternative Name: PLK2 (SNK) (PLK2 Products)

Synonyms: SNK antibody, hPlk2 antibody, hSNK antibody, Snk antibody, PLK2 antibody, Plx2 antibody, MGC53990 antibody, plk2 antibody, zgc:165644 antibody, polo like kinase 2 antibody, polo-like kinase 2 antibody, polo-like kinase 2 L homeolog antibody, polo-like kinase 2b (Drosophila) antibody, Serine/threonine-protein kinase plk-2 antibody, PLK2 antibody, Plk2 antibody, plk2.L antibody, plk2b antibody, plk2 antibody, plk-2 antibody

Background: Plks (polo-like kinases) encode serine/threonine kinases that are closely related to polo and CDC5, genes that are required for passage through mitosis in Drosophila and Saccharomyces, respectively. Polo-like kinases, which include Plk, Snk (for serum-inducible kinase, also designated Plk2) and Fnk (for FGF-inducible kinase, also designated Plk3 or PRK), play a role in cell proliferation. Plk protein accumulates in the cell during S and G2 phases of the cell cycle, and both protein content and catalytic activity peak at the onset of mitosis, followed by a rapid reduction after mitosis. Snk and Fnk are immediate-early response genes that are first expressed during G1 phase. SNK may play a role in the division of at least some cell types, such as fibroblasts, and could function in embryogenesis, wound healing or neoplasia SNK mRNA is rapidly induced in human lung fibroblasts upon reintroduction of serum following 36 hours of serum deprivation.

Molecular Weight: 78237

Gene ID: 10769

NCBI Accession: NP_001239155, NP_006613

UniProt: Q9NYY3