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TEK antibody (C-Term)

This Rabbit Polyclonal antibody specifically detects TEK in WB and IHC (p). It exhibits reactivity toward Human.
Catalog No. ABIN392059

Quick Overview for TEK antibody (C-Term) (ABIN392059)

Target

See all TEK Antibodies
TEK (TEK Tyrosine Kinase, Endothelial (TEK))

Reactivity

  • 127
  • 64
  • 50
  • 22
  • 4
  • 3
Human

Host

  • 124
  • 21
  • 4
  • 3
  • 2
Rabbit

Clonality

  • 130
  • 24
Polyclonal

Conjugate

  • 83
  • 10
  • 8
  • 5
  • 4
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 3
  • 2
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
This TEK antibody is un-conjugated

Application

  • 86
  • 58
  • 42
  • 40
  • 40
  • 32
  • 24
  • 18
  • 13
  • 12
  • 7
  • 7
  • 4
  • 2
  • 2
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone

RB01525-01526
  • Binding Specificity

    • 19
    • 19
    • 16
    • 8
    • 7
    • 6
    • 5
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 758-789, C-Term

    Predicted Reactivity

    B

    Purification

    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

    Immunogen

    This TEK (TIE2) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 758-789 amino acids from the C-terminal region of human TEK (TIE2).

    Isotype

    Ig Fraction
  • Application Notes

    WB: 1:1000. IHC-P: 1:50~100. IHC-P: 1:50~100

    Restrictions

    For Research Use only
  • Format

    Liquid

    Buffer

    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

    Preservative

    Sodium azide

    Precaution of Use

    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

    Storage

    4 °C,-20 °C

    Storage Comment

    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

    Expiry Date

    6 months
  • Target

    TEK (TEK Tyrosine Kinase, Endothelial (TEK))

    Alternative Name

    TEK (TIE2)

    Background

    The TEK receptor tyrosine kinase is expressed almost exclusively in endothelial cells in mice, rats, and humans. This receptor possesses a unique extracellular domain containing 2 immunoglobulin-like loops separated by 3 epidermal growth factor-like repeats that are connected to 3 fibronectin type III-like repeats. The ligand for the receptor is angiopoietin-1. Defects in TEK are associated with inherited venous malformations, the TEK signaling pathway appears to be critical for endothelial cell-smooth muscle cell communication in venous morphogenesis. TEK is closely related to the TIE receptor tyrosine kinase.

    Molecular Weight

    125830

    Gene ID

    7010

    NCBI Accession

    NP_000450

    UniProt

    Q02763

    Pathways

    RTK Signaling, Growth Factor Binding
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