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HCK antibody (N-Term)
HCK
Reactivity: Human
WB
Host: Rabbit
Polyclonal
RB03082
unconjugated
Product Details anti-HCK Antibody
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Target
See all HCK Antibodies
HCK
(Hemopoietic Cell Kinase (HCK))
Binding Specificity
All epitopes for HCK antibodies
AA 1-30, N-Term
Reactivity
All reactivities for HCK antibodies
Human
Host
All hosts for HCK antibodies
Rabbit
Clonality
All clonalities for HCK antibodies
Polyclonal
Conjugate
All conjugates for HCK antibodies
This HCK antibody is un-conjugated
Application
All applications for HCK antibodies
Western Blotting (WB)
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This HCK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HCK.
Clone
RB03082
Isotype
Ig Fraction
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Alternatives
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Application Details
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Application Notes
WB: 1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date
6 months
Target Details for HCK
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Target
HCK
(Hemopoietic Cell Kinase (HCK))
Alternative Name
HCK (HCK Products )
Synonyms
laloo antibody, HCK antibody, MGC107870 antibody, JTK9 antibody, p59Hck antibody, p61Hck antibody, AI849071 antibody, Bmk antibody, Hctk antibody, p56Hck antibody, HCK proto-oncogene, Src family tyrosine kinase L homeolog antibody, HCK proto-oncogene, Src family tyrosine kinase antibody, hemopoietic cell kinase antibody, hck.L antibody, HCK antibody, hck antibody, Hck antibody
Background
HCK is a protein-tyrosine kinase that is predominantly expressed in hemopoietic cell types. The encoded protein may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Alternate translation initiation site usage, including a non-AUG (CUG) codon, results in the production of two different isoforms, that have different subcellular localization.
Molecular Weight
59600
Gene ID
3055
NCBI Accession
NP_001165600 , NP_001165601 , NP_001165602 , NP_001165604 , NP_002101
UniProt
P08631
Pathways
Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Regulation of Actin Filament Polymerization , CXCR4-mediated Signaling Events , Thromboxane A2 Receptor Signaling
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