GHRH antibody (N-Term)

Catalog No. ABIN392174

The Rabbit Polyclonal anti-GHRH antibody is suitable to detect GHRH in samples from Human. It has been validated for WB, IHC (p) and IF.

Quick Overview for GHRH antibody (N-Term) (ABIN392174)

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GHRH antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)

Clone: RB14533

Product Details anti-GHRH Antibody

Binding Specificity: AA 8-34, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This GHRH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 8-34 amino acids from the N-terminal region of human GHRH.

Isotype: Ig Fraction

Application Details

Application Notes: IF: 1:10~50. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for GHRH

Target: GHRH (Growth Hormone Releasing Hormone (GHRH))

Alternative Name: GHRH

Background: GHRH belongs to the glucagon family and is a preproprotein that is produced in the hypothalamus. The preproprotein is cleaved to form a 44 aa factor, also called somatocrinin, that acts to stimulate growth hormone release from the pituitary. Variant receptors for somatocrinin have been found in several types of tumors, and antagonists of these receptors can inhibit the growth of the tumors. Defects in this protein are a cause of dwarfism, while hypersecretion of the encoded protein is a cause of gigantism.

Molecular Weight: 12447

Gene ID: 2691

NCBI Accession: NP_001171660, NP_066567

UniProt: P01286

Pathways: Hormone Transport, Hormone Activity, cAMP Metabolic Process