ACVRL1 antibody (C-Term)

Catalog No. ABIN392242

This Rabbit Polyclonal antibody specifically detects ACVRL1 in WB, FACS and IHC (p). It exhibits reactivity toward Human.

Quick Overview for ACVRL1 antibody (C-Term) (ABIN392242)

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVRL1 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB03737

Product Details anti-ACVRL1 Antibody

Binding Specificity: AA 474-503, C-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This ACVRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 474-503 amino acids from the C-terminal region of human ACVRL1.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100. FC: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for ACVRL1

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Alternative Name: ACVRL1

Background: ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

Molecular Weight: 56124

Gene ID: 94

NCBI Accession: NP_000011, NP_001070869

UniProt: P37023