ACVRL1 antibody
-
- Target See all ACVRL1 Antibodies
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
-
Reactivity
- Human
-
Host
- Rabbit
-
Clonality
- Polyclonal
-
Conjugate
- This ACVRL1 antibody is un-conjugated
-
Application
- Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
- Immunogen
- Synthesized peptide derived from internal of Human ACVL1.
- Isotype
- IgG
- Top Product
- Discover our top product ACVRL1 Primary Antibody
-
-
- Application Notes
- WB:1:500-1:3000, IHC:1:50-1:100, IF:1:100-1:500,
- Restrictions
- For Research Use only
-
- Format
- Liquid
- Buffer
- Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C,-80 °C
- Storage Comment
- Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
-
- Target
- ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))
- Alternative Name
- ACVRL1 (ACVRL1 Products)
- Synonyms
- ACVRL1 antibody, vgb antibody, alk1 antibody, zehn1109 antibody, hm:zehn1109 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, SKR3 antibody, TSR-I antibody, R-3 antibody, R3 antibody, SETHKIR antibody, AI115505 antibody, AI427544 antibody, Acvrlk1 antibody, Alk1 antibody, activin A receptor like type 1 antibody, activin A receptor type II-like 1 antibody, activin A receptor, type II-like 1 antibody, ACVRL1 antibody, acvrl1 antibody, Acvrl1 antibody
- Background
-
Background: Type I receptor for TGF-beta family ligands BMP9/GDF2 and BMP10 and important regulator of normal blood vessel development. On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. May bind activin as well.
ten Dijke P., Oncogene 8:2879-2887(1993).
Attisano L., Cell 75:671-680(1993).
Berg J.N., Am. J. Hum. Genet. 61:60-67(1997).Aliases: Activin A receptor antibody, Activin A receptor type II like 1 antibody, Activin A receptor, type II like kinase 1 antibody, Activin receptor like kinase 1 antibody, Activin receptor-like kinase 1 antibody, ACVL1_HUMAN antibody, ACVRL1 antibody, ACVRLK1 antibody, ALK-1 antibody, ALK1 antibody, HHT antibody, HHT2 antibody, ORW2 antibody, Osler Rendu Weber syndrome 2 antibody, Serine/threonine protein kinase receptor R3 antibody, Serine/threonine-protein kinase receptor R3 antibody, SKR3 antibody, TGF B superfamily receptor type I antibody, TGF-B superfamily receptor type I antibody, TSR-I antibody, TSR1 antibody
- UniProt
- P37023
-