ACVRL1 antibody (AA 38-68)

Catalog No. ABIN3029853

The Rabbit Polyclonal anti-ACVRL1 antibody (ABIN3029853) specifically detects ACVRL1 in WB, ELISA, IHC and FACS. The antibody is reactive with Human and Mouse samples.

Quick Overview for ACVRL1 antibody (AA 38-68) (ABIN3029853)

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ACVRL1 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-ACVRL1 Antibody

Binding Specificity: AA 38-68

Purification: Purified

Immunogen: A portion of amino acids 38-68 from the human protein was used as the immunogen for this ALK1 antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the ALK1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Flow Cytometry: 1:10-1:50,IHC (Paraffin): 1:50-1:100,Western blot: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the ALK1 antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Target Details for ACVRL1

Target: ACVRL1 (Activin A Receptor Type II-Like 1 (ACVRL1))

Alternative Name: ALK1

Background: ACVRL1 is a type I cell-surface receptor for the TGF-beta superfamily of ligands. It shares with other type I receptors a high degree of similarity in serine-threonine kinase subdomains, a glycine- and serine-rich region (called the GS domain) preceding the kinase domain, and a short C-terminal tail. This protein, sometimes termed ALK1, shares similar domain structures with other closely related ALK or activin receptor-like kinase proteins that form a subfamily of receptor serine/threonine kinases. Mutations in this gene are associated with hemorrhagic telangiectasia type 2, also known as Rendu-Osler-Weber syndrome 2.

UniProt: P37023