PAK2 antibody (N-Term)

Catalog No. ABIN392433

The Rabbit Polyclonal anti-PAK2 antibody (Clone RB1221-1222) (ABIN392433) specifically detects PAK2 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for PAK2 antibody (N-Term) (ABIN392433)

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PAK2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB1221-1222

Product Details anti-PAK2 Antibody

Binding Specificity: AA 192-222, N-Term

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This PAK2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 192-222 amino acids from the N-terminal region of human PAK2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for PAK2

Target: PAK2 (P21-Activated Kinase 2 (PAK2))

Alternative Name: PAK2

Background: PAK2, a member of the STE20 subfamily of Ser/Thr protein kinases, acts on a variety of targets. It phosphorylates ribosomal protein S6, histone H4 and myelin basic protein. PAK2 interacts tightly with GTP-bound but not GDP-bound CDC42/p21 and RAC1. Expression is ubiquitous, with higher levels seen in skeletal muscle, ovary, thymus and spleen. PAK2 is autophosphorylated when activated by CDC42/p21. The protein structure contains 1 CRIB domain.

Molecular Weight: 58043

Gene ID: 5062

NCBI Accession: NP_002568

UniProt: Q13177

Pathways: MAPK Signaling, RTK Signaling, TCR Signaling, Fc-epsilon Receptor Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha