Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

PLK3 antibody (C-Term)

PLK3 Reactivity: Human, Mouse WB Host: Rabbit Polyclonal RB0875 unconjugated
Catalog No. ABIN392602
  • Target See all PLK3 Antibodies
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Binding Specificity
    • 8
    • 7
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 615-646, C-Term
    Reactivity
    • 45
    • 23
    • 9
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Mouse
    Host
    • 41
    • 2
    • 2
    Rabbit
    Clonality
    • 45
    Polyclonal
    Conjugate
    • 23
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This PLK3 antibody is un-conjugated
    Application
    • 37
    • 29
    • 20
    • 5
    • 1
    • 1
    Western Blotting (WB)
    Predicted Reactivity
    Rat
    Purification
    This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
    Immunogen
    This PLK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 615-646 amino acids from the C-terminal region of human PLK3.
    Clone
    RB0875
    Isotype
    Ig Fraction
    Top Product
    Discover our top product PLK3 Primary Antibody
  • Application Notes
    WB: 1:1000
    Restrictions
    For Research Use only
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C,-20 °C
    Storage Comment
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Expiry Date
    6 months
  • Zhang, Shi, Paddon, Hampong, Dai, Pelech: "B23/nucleophosmin serine 4 phosphorylation mediates mitotic functions of polo-like kinase 1." in: The Journal of biological chemistry, Vol. 279, Issue 34, pp. 35726-34, (2004) (PubMed).

  • Target
    PLK3 (Polo-Like Kinase 3 (PLK3))
    Alternative Name
    PLK3 (PLK3 Products)
    Synonyms
    cnk antibody, wu:fi35f10 antibody, fnk antibody, prk antibody, plx3 antibody, MGC89507 antibody, PLK2/3 antibody, NV15469 antibody, Plx3 antibody, CNK antibody, FNK antibody, PRK antibody, Cnk antibody, Fnk antibody, polo-like kinase 3 (Drosophila) antibody, polo like kinase 3 antibody, polo-like kinase 3 antibody, polo-like kinase 3 S homeolog antibody, polo-like kinase 3 L homeolog antibody, Serine/threonine-protein kinase plk-3 antibody, plk3 antibody, PLK3 antibody, LOC100118436 antibody, plk3.S antibody, plk3.L antibody, Plk3 antibody, plk-3 antibody
    Background
    CNK, a member of the CDC5/Polo subfamily of Ser/Thr protein kinases, is involved in regulating M phase functions during the cell cycle. It may also be part of the signaling network controlling cellular adhesion. In vitro, is able to phosphorylate CDC25C and casein. This membrane-associated protein binds to the calcium/integrin-binding protein (CIB). This interaction probably occurs via the POLO-box domain. Transcripts are highly detected in placenta, lung, followed by skeletal muscle, heart, pancreas, ovaries and kidney and weakly detected in liver and brain. This protein exhibits a short half-live. In cells of hematopoietic origin, CNK is strongly and exclusively detected in terminally differentiated macrophages. Transcript expression appears to be down-regulated in primary lung tumor. Cytokine and cellular adhesion trigger CNK induction. CNK is thought to be phosphorylated as cells enter mitosis and dephosphorylated as cells exit mitosis The protein contains 2 POLO box domains.
    Molecular Weight
    71629
    Gene ID
    1263
    NCBI Accession
    NP_004064
    UniProt
    Q9H4B4
    Pathways
    Regulation of long-term Neuronal Synaptic Plasticity
You are here:
Support