TRPM8 antibody (AA 521-552)

Catalog No. ABIN392820

The Rabbit Polyclonal anti-TRPM8 antibody (Clone RB14417) (ABIN392820) specifically detects TRPM8 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for TRPM8 antibody (AA 521-552) (ABIN392820)

Target: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRPM8 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB14417

Product Details anti-TRPM8 Antibody

Binding Specificity: AA 521-552

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TRPM8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 521-552 amino acids from the Central region of human TRPM8.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for TRPM8

Target: TRPM8 (Transient Receptor Potential Cation Channel, Subfamily M, Member 8 (TRPM8))

Alternative Name: TRPM8

Background: TRPM8 is a receptor-activated non-selective cation channel involved in detection of sensations such as coolness, by being activated by cold temperature below 25 degrees Celsius. It is activated by icilin, eucalyptol, menthol, cold and modulation of intracellular pH and involved in menthol sensation. It is permeable for monovalent cations sodium, potassium, and cesium and divalent cation calcium.

Molecular Weight: 127685

Gene ID: 79054

NCBI Accession: NP_076985

UniProt: Q7Z2W7