DUSP7 antibody (N-Term)

Catalog No. ABIN392865

The Rabbit Polyclonal anti-DUSP7 antibody (Clone RB5816) (ABIN392865) specifically detects DUSP7 in WB and IHC (p). The antibody is reactive with Human samples.

Quick Overview for DUSP7 antibody (N-Term) (ABIN392865)

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This DUSP7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB5816

Product Details anti-DUSP7 Antibody

Binding Specificity: AA 96-127, N-Term

Predicted Reactivity: M, Rat

Purification: This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.

Immunogen: This DUSP7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 96-127 amino acids from the N-terminal region of human DUSP7.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:50~100

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 6 months

Target Details for DUSP7

Target: DUSP7 (Dual Specificity Phosphatase 7 (DUSP7))

Alternative Name: DUSP7

Background: DUSP7 is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP)kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli.

Molecular Weight: 44957

Gene ID: 1849

NCBI Accession: NP_001938

UniProt: Q16829

Pathways: Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades