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TDP1 antibody (N-Term)

TDP1 Reactivity: Human WB, IHC (p), EIA Host: Mouse Monoclonal AT1F2 unconjugated
Catalog No. ABIN400858
  • Target See all TDP1 Antibodies
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Binding Specificity
    • 7
    • 7
    • 7
    • 6
    • 6
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-298, N-Term
    Reactivity
    • 42
    • 15
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    Human
    Host
    • 35
    • 7
    • 1
    Mouse
    Clonality
    • 38
    • 5
    Monoclonal
    Conjugate
    • 29
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    This TDP1 antibody is un-conjugated
    Application
    • 36
    • 22
    • 10
    • 8
    • 7
    • 6
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    The antibody recognizes human TDP1. Other species not tested.
    Characteristics
    Synonyms: Tyrosyl-DNA phosphodiesterase 1
    Purification
    Protein-G affinity chromatography
    Immunogen
    Recombinant human TDP1 (1-298 aa) purified from E. coli
    Clone
    AT1F2
    Isotype
    IgG2b
    Top Product
    Discover our top product TDP1 Primary Antibody
  • Application Notes
    ELISA. Western blot: 1/1,000-1/2,000. Immunohistochemistry on Paraffin Sections: 5 μg/mL
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1.0 mg/mL
    Buffer
    PBS, pH 7.4, containing 0.09 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for up to two weeks or (in aliquots) at -20 °C or -70 °Cfor longer. Avoid repeated freezing and thawing.
    Shelf life: one year from despatch.
    Expiry Date
    12 months
  • Target
    TDP1 (Tyrosyl-DNA Phosphodiesterase 1 (TDP1))
    Alternative Name
    TDP1 (TDP1 Products)
    Synonyms
    2810481F14Rik antibody, 4921509N21Rik antibody, AI838772 antibody, AW493413 antibody, E430034L06Rik antibody, MLZ-501 antibody, SCAN1 antibody, tdp1 antibody, MGC83708 antibody, TDP1 antibody, F8M21.60 antibody, F8M21_60 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA phosphodiesterase 1 antibody, tyrosyl-DNA Phosphodiesterase (Tdp1) antibody, tyrosyl-DNA phosphodiesterase 1 L homeolog antibody, tyrosyl-DNA phosphodiesterase-like protein antibody, TDP1 antibody, Tc00.1047053511191.10 antibody, Tdp1 antibody, tdp1.L antibody, tdp1 antibody, PTRG_11198 antibody, MCYG_02121 antibody, MGYG_03035 antibody
    Background
    Tyrosyl-DNA phosphodiesterase (TDP1) is a DNA repair enzyme that catalyzes the hydrolysis of a phophodiester bond between a tyrosine residue and a DNA 3' phosphate. This protein is a member of the phospholipase D (PLD) superfamily and contains two PLD phosphodiesterase domains. Mutations in TDP1 are associated with the disease spinocerebellar ataxia with axonal neuropathy (SCAN1) by interfering with DNA transcription or by inducting apoptosis in postmitotic neurons.Synonyms: Tyrosyl-DNA phosphodiesterase 1
    Gene ID
    55775
    UniProt
    Q9NUW8
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