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FANCE antibody (N-Term)
FANCE
Reactivity: Human
EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-FANCE Antibody
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Target
See all FANCE Antibodies
FANCE
(Fanconi Anemia, Complementation Group E (FANCE))
Binding Specificity
All epitopes for FANCE antibodies
AA 1-13, N-Term
Reactivity
All reactivities for FANCE antibodies
Human
Host
All hosts for FANCE antibodies
Rabbit
Clonality
All clonalities for FANCE antibodies
Polyclonal
Conjugate
All conjugates for FANCE antibodies
This FANCE antibody is un-conjugated
Application
All applications for FANCE antibodies
Enzyme Immunoassay (EIA)
Sequence
M-A-T-P-D-A-G-L-P-G-A-E-G-C
Specificity
This antibody detects FANCE.
Cross-Reactivity (Details)
Species reactivity (tested):Human.
Purification
Immunoaffinity chromatography
Immunogen
Synthetic peptide corresponding to amino acids 1-13 of Human FANCE
Isotype
IgG
Top Product
Discover our top product FANCE Primary Antibody
Alternatives
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Application Details
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Application Notes
ELISA: 1: 4,000 to 1: 18,000. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL (by UV absorbance at 280 nm)
Buffer
0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2, 0.01 % (w/v) Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing. Should this product contain a precipitate we recommend microcentrifugation before use.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.
Target Details for FANCE
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Target
FANCE
(Fanconi Anemia, Complementation Group E (FANCE))
Alternative Name
FANCE (FANCE Products )
Synonyms
FANCE antibody, fae antibody, face antibody, FACE antibody, FAE antibody, 2810451D06Rik antibody, AI415634 antibody, AW209126 antibody, RGD1561045 antibody, Fanconi anemia complementation group E antibody, Fanconi anemia, complementation group E antibody, FANCE antibody, fance antibody, Fance antibody
Background
FANCE promotes the nuclear accumulation of FANCC. FANCE protein is part of the FA nuclear complex, binding FANCC & FANCD2. It is required for the nuclear accumulation of FANCC and provides a bridge between the FA complex and FANCD2. FANCC mutants do not bind FANCE or prevent chromosome breakage.Synonyms: FACE, Fanconi anemia group E protein
Gene ID
2178
NCBI Accession
NP_068741
UniProt
Q9HB96
Pathways
DNA Damage Repair
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