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PTENP1 antibody (N-Term)

PTENP1 Reactivity: Human, Chimpanzee, Dog, Green Pufferfish, Macaque, Mouse, Rat, Zebrafish (Danio rerio) WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN401437
  • Target See all PTENP1 products
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Binding Specificity
    • 2
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reactivity
    Human, Chimpanzee, Dog, Green Pufferfish, Macaque, Mouse, Rat, Zebrafish (Danio rerio)
    Host
    • 2
    • 2
    Rabbit
    Clonality
    • 4
    Polyclonal
    Conjugate
    • 4
    This PTENP1 antibody is un-conjugated
    Application
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse, Rat, Canine, Macaque, Chimpanzee, Opossum, Zebrafish, Green pufferfish, Platypus.
    Species reactivity (tested):Human.
    Purification
    Affinity chromatography
    Immunogen
    Purified peptide corresponding to amino acids near the N-terminal end of human PTEN-P1 protein
    Isotype
    IgG
  • Application Notes
    ELISA: 1/160,000. Western Blot: 1/500 to 1/2,000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    0.73 mg/mL (by UV absorbance at 280 nm)
    Buffer
    0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2 containing 0.01 % (w/v) Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    -20 °C
  • Target
    PTENP1 (Phosphatase and Tensin Homolog Pseudogene 1 (PTENP1))
    Alternative Name
    PTENP1 (PTENP1 Products)
    Synonyms
    PTEN-rs antibody, PTEN2 antibody, PTENpg1 antibody, PTH2 antibody, psiPTEN antibody, phosphatase and tensin homolog pseudogene 1 antibody, PTENP1 antibody
    Background
    This gene (PTENP1) is a highly homologous pseudogene of PTEN. PTEN was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. PTEN is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tension like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. It negatively regulates intracellular levels of phosphatidylinositol-3,4,5-trisphosphate in cells and functions as a tumor suppressor by negatively regulating AKT/PKB signaling pathway.Synonyms: PTEN-rs, PTEN2, PTH2, Phosphatase and tensin homolog 2, Phosphatase and tensin homolog pseudogene 1, psiPTEN
    Gene ID
    9606
    UniProt
    O43460
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