Cathepsin E antibody (Middle Region)

Catalog No. ABIN452887

Product Details anti-Cathepsin E Antibody

Target: Cathepsin E (CTSE)

Binding Specificity: Middle Region

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Cathepsin E antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects Cathepsin E at Center.

Cross-Reactivity (Details): Species reactivity (tested):Human, Mouse

Purification: Prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human CTSE

Application Details

Application Notes: Western blot: 1: 50 - 1: 100. ELISA: 1: 1,000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody at 2 - 8 °C up to one month or (in aliquots) at -20 °C for longer.

Target Details for Cathepsin E

Target: Cathepsin E (CTSE)

Alternative Name: Cathepsin E (CTSE Products)

Synonyms: CATE antibody, A430072O03Rik antibody, C920004C08Rik antibody, CE antibody, CatE antibody, CEA antibody, CEB antibody, Ctsea antibody, CTSE antibody, ce1 antibody, ce2 antibody, cate antibody, CE1 antibody, ce1-A antibody, ctse antibody, CE2 antibody, ce2-A antibody, cathepsin E antibody, cathepsin E L homeolog antibody, cathepsin E S homeolog antibody, CTSE antibody, Ctse antibody, TP03_0056 antibody, Smp_184930 antibody, ctse antibody, ctse.L antibody, ctse.S antibody

Background: CTSE is a gastric aspartyl protease that functions as a disulfide-linked homodimer. This protease, which is a member of the peptidase C1 family, has a specificity similar to that of pepsin A and cathepsin D. It is an intracellular proteinase that does not appear to be involved in the digestion of dietary protein and is found in highest concentration in the surface of epithelial mucus-producing cells of the stomach. It is the first aspartic proteinase expressed in the fetal stomach and is found in more than half of gastric cancers. It appears, therefore, to be an oncofetal antigen.Synonyms: CTSE

Molecular Weight: 43312 Da

Gene ID: 1510

NCBI Accession: NP_001901

UniProt: P14091