PHGDH antibody (N-Term)

Catalog No. ABIN453266

The Rabbit Polyclonal anti-PHGDH antibody has been validated for WB and EIA. It is suitable to detect PHGDH in samples from Human.

Quick Overview for PHGDH antibody (N-Term) (ABIN453266)

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHGDH antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-PHGDH Antibody

Binding Specificity: N-Term

Specificity: This antibody reacts to PHGDH.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the N-terminal region of human PHGDH

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for PHGDH

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Alternative Name: PHGDH

Background: 3-Phosphoglycerate dehydrogenase catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.Synonyms: 3-PGDH, D-3-phosphoglycerate dehydrogenase, PGDH3

Gene ID: 26227

NCBI Accession: NP_006614

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, Warburg Effect