PHGDH antibody (AA 140-168)

Catalog No. ABIN3032221

This Rabbit Polyclonal antibody specifically detects PHGDH in WB, ELISA, IHC and FACS. It exhibits reactivity toward Human and Mouse.

Quick Overview for PHGDH antibody (AA 140-168) (ABIN3032221)

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PHGDH antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Flow Cytometry (FACS)

Product Details anti-PHGDH Antibody

Binding Specificity: AA 140-168

Purpose: PHGDH Antibody

Cross-Reactivity (Details): Expected species reactivity: Bovine, Pig, Primate

Purification: Purified

Immunogen: A portion of amino acids 140-168 from the human protein was used as the immunogen for this PHGDH antibody.

Isotype: Ig Fraction

Application Details

Application Notes: Titration of the PHGDH antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: In 1X PBS, pH 7.4, with 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Aliquot the PHGDH antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Target Details for PHGDH

Target: PHGDH (phosphoglycerate Dehydrogenase (PHGDH))

Alternative Name: PHGDH

Background: 3-Phosphoglycerate dehydrogenase catalyzes the transition of 3-phosphoglycerate into 3-phosphohydroxypyruvate, which is the first and rate-limiting step in the phosphorylated pathway of serine biosynthesis, using NAD+/NADH as a cofactor.

UniProt: O43175

Pathways: Metabolism of Steroid Hormones and Vitamin D, Warburg Effect