Prosaposin antibody (Middle Region)

Catalog No. ABIN453360

This anti-Prosaposin antibody is a Rabbit Polyclonal antibody detecting Prosaposin in WB and EIA. Suitable for Human.

Quick Overview for Prosaposin antibody (Middle Region) (ABIN453360)

Target: Prosaposin (PSAP)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Prosaposin antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-Prosaposin Antibody

Binding Specificity: Middle Region

Specificity: This antibody reacts to SAP.

Purification: Saturated Ammonium Sulfate (SAS) precipitation

Immunogen: KLH conjugated synthetic peptide selected from the Center region of human SAP

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/50 - 1/100.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for Prosaposin

Target: Prosaposin (PSAP)

Alternative Name: PSAP

Background: PSAP is a highly conserved glycoprotein which is a precursor for 4 cleavage products: saposins A, B, C, and D. Each domain of the precursor protein is approximately 80 amino acid residues long with nearly identical placement of cysteine residues and glycosylation sites. Saposins A-D localize primarily to the lysosomal compartment where they facilitate the catabolism of glycosphingolipids with short oligosaccharide groups. The precursor protein exists both as a secretory protein and as an integral membrane protein and has neurotrophic activities.Synonyms: GLBA, Proactivator polypeptide, Prosaposin, SAP1

Gene ID: 5660

NCBI Accession: NP_001035930

UniProt: P07602

Pathways: Positive Regulation of Endopeptidase Activity