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IL-8 antibody (C-Term)

IL8 Reactivity: Human WB, FACS, IHC (p), EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN453704
  • Target See all IL-8 (IL8) Antibodies
    IL-8 (IL8) (Interleukin 8 (IL8))
    Binding Specificity
    • 45
    • 17
    • 7
    • 6
    • 6
    • 6
    • 5
    • 5
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    C-Term
    Reactivity
    • 127
    • 22
    • 15
    • 13
    • 12
    • 12
    • 10
    • 9
    • 9
    • 6
    • 4
    • 4
    • 4
    • 3
    • 3
    • 1
    Human
    Host
    • 118
    • 96
    • 7
    • 3
    • 3
    • 3
    • 1
    Rabbit
    Clonality
    • 134
    • 97
    Polyclonal
    Conjugate
    • 123
    • 48
    • 28
    • 9
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    This IL-8 antibody is un-conjugated
    Application
    • 156
    • 101
    • 78
    • 36
    • 33
    • 24
    • 16
    • 16
    • 15
    • 13
    • 10
    • 8
    • 8
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
    Specificity
    This antibody recognizes Interleukin-8/IL8.
    Purification
    Saturated Ammonium Sulfate (SAS) precipitation
    Immunogen
    KLH conjugated synthetic peptide selected from the C-terminal region of human IL8
    Isotype
    Ig Fraction
    Top Product
    Discover our top product IL8 Primary Antibody
  • Application Notes
    ELISA: 1/1,000. Western blotting: 1/50-1/100.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    0.25 mg/mL
    Buffer
    PBS with 0.09 % (W/V) Sodium Azide as preservative.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    IL-8 (IL8) (Interleukin 8 (IL8))
    Alternative Name
    Interleukin-8 / IL8 (IL8 Products)
    Synonyms
    CXCL8 antibody, GCP-1 antibody, GCP1 antibody, LECT antibody, LUCT antibody, LYNAP antibody, MDNCF antibody, MONAP antibody, NAF antibody, NAP-1 antibody, NAP1 antibody, IL-8 antibody, AMCF-I antibody, il8 antibody, IL8 antibody, si:dkey-151b16.2 antibody, cxcli2 antibody, cxcl8 antibody, gcp-1 antibody, il-8 antibody, lynap antibody, mdncf antibody, monap antibody, nap-1 antibody, C-X-C motif chemokine ligand 8 antibody, interleukin 8 antibody, chemokine (C-X-C motif) ligand 8a antibody, chemokine (C-X-C motif) ligand 1-like antibody, chemokine (C-X-C motif) ligand 8 L homeolog antibody, CXCL8 antibody, il8 antibody, cxcl8a antibody, IL8 antibody, Cxcl8 antibody, LOC422654 antibody, cxcl8.L antibody
    Background
    Interleukin 8, IL8 is a member of the CXC chemokine family. This family of small basic heparan-binding proteins are proinflammatory and primarily mediate the activation and migration of neutrophils into tissue from peripheral blood. This chemokine is one of the major mediators of the inflammatory response and is secreted by several cell types in response to an inflammatory stimulus. It functions as a chemoattractant, and is also a potent angiogenic factor. IL8 attracts neutrophils, basophils, and T-cells, but not monocytes. Cystic fibrosis (CF) is characterized by severe lung inflammation. The inflammatory process is believed to be caused by massive overproduction of the proinflammatory protein IL8, and the high levels of IL8 in the CF lung are therefore believed to be the central mechanism behind CF lung pathophysiology.Synonyms: CXCL8, Emoctakin, GCP1, Granulocyte chemotactic protein 1, MDNCF, MONAP, Monocyte-derived neutrophil chemotactic factor, Monocyte-derived neutrophil-activating peptide, NAP1, Neutrophil-activating protein 1, Protein 3-10C, T-cell chemotactic factor
    Gene ID
    3576
    NCBI Accession
    NP_000575
    UniProt
    P10145
    Pathways
    TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Hepatitis C, Autophagy
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