XPA antibody (C-Term)

Catalog No. ABIN453876

The Rabbit Polyclonal anti-XPA antibody (ABIN453876) specifically detects XPA in WB and EIA. The antibody is reactive with Human samples.

Quick Overview for XPA antibody (C-Term) (ABIN453876)

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This XPA antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Product Details anti-XPA Antibody

Binding Specificity: C-Term

Specificity: This antibody reacts to XPAC.

Purification: Affinity chromatography on Protein A

Immunogen: conjugated synthetic peptide selected from the C-term region of human XPA

Application Details

Application Notes: ELISA: 1/1,000. Western blotting: 1/100 - 1/500.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.25 mg/mL

Buffer: PBS with 0.09 % (W/V) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Target Details for XPA

Target: XPA (Xeroderma Pigmentosum, Complementation Group A (XPA))

Alternative Name: XPA / XPAC

Background: XPA is involved in DNA excision repair. It initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. This protein is required for UV-induced CHK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers (CPD), sites of DNA damage after UV irradiation.Synonyms: DNA repair protein complementing XP-A cells, Xeroderma pigmentosum group A-complementing protein

Gene ID: 7507

NCBI Accession: NP_000371

UniProt: P23025

Pathways: DNA Damage Repair