IL16 antibody (HRP)

Catalog No. ABIN453906

The HRP-conjugated Mouse Monoclonal anti-IL16 antibody (Clone 323) (ABIN453906) specifically detects IL16 in EIA. The antibody is reactive with Human samples.

Quick Overview for IL16 antibody (HRP) (ABIN453906)

Target: IL16 (Interleukin 16 (IL16))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This IL16 antibody is conjugated to HRP

Application: Enzyme Immunoassay (EIA)

Clone: 323

Product Details anti-IL16 Antibody (HRP)

Specificity: This antibody reacts with natural and recombinant IL-16. No cross-reactivity with Human Serum Albumin, Bovine Serum Albumin and other cytokines or growth factors tested such as IL-1beta, TGF-beta1, TNF-alpha, IL-8, IL-7, MCP-1, EGF, bFGF, GM-CSF.

Purification: Affinity chromatography on Protein G

Immunogen: Purified recombinant human IL-16

Isotype: IgG2a

Application Details

Application Notes: ELISA.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 0.01 M PBS, pH 7.0 ± 0.1 in 50 % Glycerol and 0.01 % Thimerosal as a bacteriostat

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody at -20 °C. Can be shipped at 2 - 8 °C.

Target Details for IL16

Target: IL16 (Interleukin 16 (IL16))

Alternative Name: Interleukin-16 / IL16

Background: IL16 is a proinflammatory cytokine that is chemotactic for CD4+ T lymphocytes, monocytes, and eosinophils. IL16 is synthesized as a precursor molecule (pro IL16) of approximately 68 kDa and 631 amino acid residues lacking a signal peptide. The sequence and structure of IL16 is conserved across species. In addition to inducing chemotaxis, IL16 upregulates the IL2 receptor and upregulates HLADR expression. It also inhibits T cell receptor (TCR)/CD3 dependent activation, and suppresses HIV1 replication in vitro. Sources of IL16 include epithelial cells, mast cells, T lymphocytes (CD4+ and CD8+), macrophages, synovial fibroblasts, and eosinophils.Synonyms: IL-16, LCF, Lymphocyte chemoattractant factor

Gene ID: 3603

NCBI Accession: NP_004504

UniProt: Q14005