HCV 1b NS5B antibody (AA 1-14)

Catalog No. ABIN457558

This Mouse Monoclonal antibody specifically detects HCV 1b NS5B in ELISA and IP. It exhibits reactivity toward Hepatitis C Virus (HCV).

Quick Overview for HCV 1b NS5B antibody (AA 1-14) (ABIN457558)

Target: HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))

Reactivity: Hepatitis C Virus (HCV)

Host: Mouse

Clonality: Monoclonal

Conjugate: This HCV 1b NS5B antibody is un-conjugated

Application: ELISA, Immunoprecipitation (IP)

Clone: 8B2

Product Details anti-HCV 1b NS5B Antibody

Binding Specificity: AA 1-14

Sequence: SMSYTWTGAL ITPC

Specificity: Human, HCV subtype 1b NS5B

Purification: purifiedby protein G affinity chromatography

Immunogen: Recombinant Hepatitis C Virus subtype 1b nonstructuralprotein 5B (NS5B) RNA-dependent RNA polymerase (RdRp)

Isotype: IgG1

Application Details

Application Notes: ELISA titer 1:1000, Immunoprecipitation. Optimal conditions for IP should be determined for each particular application. Very weak antigen recognition in WB Blocks theRNA-dependent RNA polymerase activity in vitro. Monoclonal antibody working titer has to be established practically for each particular antigen and assay format.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/ml

Buffer: PBS pH 7.4, with 0.1%

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Divide antibodyinto aliquots prior usage. Avoid multiple freeze-thaw cycles as productdegradation may result.

Storage: -20 °C

Storage Comment: This product is shipped in non-frozen liquid form in ambient conditions

Target Details for HCV 1b NS5B

Target: HCV 1b NS5B (HCV NS5b) (Hepatitis C Virus NS5b (HCV NS5b))

Target Type: Viral Protein

Background: Non-structural protein 5B (NS5B)represents the RNA-dependent RNA polymerase (RdRp) of Hepatitis C Virus, whichis a small positive strand RNA virus in the family Flaviviridae. HCV is a major causative agent of acute and chronichepatitis, hepatocellular carcinoma and liver cirrhosis. The single subunitRNA-dependent RNA polymerase is absolutely essential for the viral replication.

UniProt: Q9WMX2