SGPL1 antibody

Catalog No. ABIN4620338

The Rabbit Polyclonal anti-SGPL1 antibody (ABIN4620338) specifically detects SGPL1 in WB. The antibody is reactive with Human, Mouse, Rat and Cow samples.

Quick Overview for SGPL1 antibody (ABIN4620338)

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Reactivity: Human, Mouse, Rat, Cow

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SGPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SGPL1 Antibody

Specificity: This antibody recognizes Sphingosine 1-Phosphate Lyase 1.

Purification: Affinity Purified

Immunogen: Synthetic peptide derived from the sphingosine 1-phosphate lyase 1 protein.

Isotype: IgG

Application Details

Application Notes: Western Blot: 1: 400.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Buffer: PBS, 0.08 % Sodium Azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: The antibody can be shipped on dry ice. Store (in aliquots) at -20 °C only.

Target Details for SGPL1

Target: SGPL1 (Sphingosine-1-Phosphate Lyase 1 (SGPL1))

Alternative Name: SGPL1

Background: Sphingosine-1-phosphate lyase cleaves phosphorylated sphingoid bases, such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis. The catalytic activity of sphingosine 1-phosphate lyase converts sphingosine 1-phosphate to phosphoethanolamine and palmitaldehyde using Pyridoxal phosphate as a co-factor. Sphingosine 1-phosphate lyase is a type III membrane protein found in the endoplasmic reticulum. Sphingosine 1-phosphate lyase is found primarily in the liver and kidney. Sphingosine 1-phosphate lyase belongs to the group II decarboxylase family.Synonyms: KIAA1252, SP-lyase 1, SPL 1, Sphingosine-1-phosphate aldolase, Sphingosine-1-phosphate lyase 1

Gene ID: 8879

NCBI Accession: NP_003892

UniProt: O95470

Pathways: Platelet-derived growth Factor Receptor Signaling