MCL-1 antibody

Catalog No. ABIN462372

The Rabbit Polyclonal anti-MCL-1 antibody (ABIN462372) specifically detects MCL-1 in WB, IHC, IF and IHC (p). The antibody is reactive with Human, Dog, Pig, Monkey, Rabbit and Guinea Pig samples.

Quick Overview for MCL-1 antibody (ABIN462372)

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Reactivity: Human, Dog, Pig, Monkey, Rabbit, Guinea Pig

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MCL-1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-MCL-1 Antibody

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide derived from the sequence of human Mcl-1, conjugated to KLH.

Type of Immunogen: Synthetic peptide - KLH conjugated

Application Details

Application Notes: Approved: IF, IHC, IHC-P (10 μg/mL), WB

Usage: Immunohistochemistry: This antibody was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in  pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for this antibody was determined to be 10 μg/mL.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.09 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C.

Target Details for MCL-1

Target: MCL-1 (MCL1) (Induced Myeloid Leukemia Cell Differentiation Protein Mcl-1 (MCL1))

Alternative Name: MCL1 / MCL 1

Background: Name/Gene ID: MCL1

Synonyms: MCL1, BCL2L3, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, Bcl2-L-3, MCL1S, MCL1L, Myeloid cell leukemia ES, MCL 1, MCL1-ES, TM, EAT, Mcl-1

Gene ID: 4170

UniProt: Q07820

Pathways: MAPK Signaling