EBV LMP2A antibody

Catalog No. ABIN644979

The Rat not_set anti-EBV LMP2A antibody (ABIN644979) specifically detects EBV LMP2A in IHC (p) and WB. The antibody is reactive with Epstein-Barr Virus (EBV) samples.

Quick Overview for EBV LMP2A antibody (ABIN644979)

Target: EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))

Reactivity: Epstein-Barr Virus (EBV)

Host: Rat

Conjugate: This EBV LMP2A antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)

Product Details anti-EBV LMP2A Antibody

Specificity: DS-MB-03627 recognizes latent membrane protein 2A (LMP2A) of Epstein-Barr virus (EBV). EBV is a human herpes virus, which is associated with conditions such as Hodgkin's disease and Burkitt's Lymphoma and is the causative agent in mononucleosis in adolescents. EBV latently infects B lymphocytes. Infected B cells express EBV nuclear antigens and latent proteins LMP1, LMP2A and LMP2B. LMP2A forms aggregates in the plasma membranes of B lymphocytes, where it functions as a negative regulator of the Src and Syk protein tyrosine kinases. Studies show that LMP2A blocks B-cell receptor (BCR) signal transduction in EBV immortalized B cells in vitro and may play an important role in maintaining a latent EBV infection within the peripheral blood B cells of infected individuals. DS-MB-03627 specifically recognizes LMP2A and does not cross react with LMP2B.

Characteristics: Rat Anti-Epstein-Barr Virus LMP2A

Purification: Purified

Immunogen: Bacterial TrpE-LMP2A fusion protein

Isotype: IgG2a

Application Details

Restrictions: For Research Use only

Handling

Concentration: IgG concentration 1.0 mg/ml

Buffer: Phosphate buffered saline

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for EBV LMP2A

Target: EBV LMP2A (Epstein-Barr Virus Latent Membrane Protein 2A (EBV LMP2A))

Alternative Name: Epstein-Barr Virus LMP2A

Target Type: Viral Protein