COX11 antibody (AA 51-100)

Catalog No. ABIN484982

The Rabbit Polyclonal anti-COX11 antibody is suitable to detect COX11 in samples from Human and Mouse. It has been validated for ELISA, WB, IHC and IF.

Quick Overview for COX11 antibody (AA 51-100) (ABIN484982)

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COX11 antibody is un-conjugated

Application: ELISA, Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Product Details anti-COX11 Antibody

Binding Specificity: AA 51-100

Purpose: COX11 Antibody

Specificity: COX11 Polyclonal Antibody detects endogenous levels of COX11 protein.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Purity: > 95 %

Immunogen: The antiserum was produced against synthesized peptide derived from human COX11. AA range:51-100

Isotype: IgG

Application Details

Application Notes: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C/1 year

Expiry Date: 12 months

Target Details for COX11

Target: COX11 (COX11 Cytochrome C Oxidase Assembly (COX11))

Alternative Name: COX11

Background:

Synonyms: COX11, Cytochrome c oxidase assembly protein COX11, mitochondrial

Background: Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes a protein which is not a structural subunit, but may be a heme A biosynthetic enzyme involved in COX formation, according to the yeast mutant studies. However, the studies in Rhodobacter sphaeroides suggest that this gene is not required for heme A biosynthesis, but required for stable formation of the Cu(B) and magnesium centers of COX. This human protein is predicted to c

Gene Name: COX11

Protein Name: Cytochrome c oxidase assembly protein COX11 mitochondrial

Molecular Weight: 31 kDa

Gene ID: 1353

OMIM: 603648

UniProt: Q9Y6N1

Pathways: Regulation of Carbohydrate Metabolic Process