ATM antibody (AA 992-1144) (FITC)

Catalog No. ABIN4880063

This anti-ATM antibody is a Mouse Monoclonal antibody detecting ATM in . Suitable for Human.

Quick Overview for ATM antibody (AA 992-1144) (FITC) (ABIN4880063)

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This ATM antibody is conjugated to FITC

Application: Please inquire

Clone: 11G12

Product Details anti-ATM Antibody (FITC)

Binding Specificity: AA 992-1144

Specificity: This antibody recognises ataxia telangiectasia mutated (ATM), a 370 kDa serine protein kinase. The ATM protein is a member of the phosphatidylinositol-3 kinase family of proteins that respond to DNA damage by phosphorylating key substrates involved in DNA repair and/or cell cycle control.

Purification: Purified on protein A from tissue culture supernatant.

Immunogen: Fusion protein corresponding to amino acid residues 992-1144 of ATM

Isotype: IgG1

Application Details

Application Notes: Optimal antibody dilution should be determined by titration

Comment:

Myeloma, fusion partnersCells from immunized mice were fused with the Sp2/0-Ag.14 myeloma cell line

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Purified IgG conjugated to Fluoroscein using Innova Biosciences Lightning-Link ®, supplied in Phosphate buffered saline (PBS) containing 0.09 % Sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Target Details for ATM

Target: ATM (Ataxia Telangiectasia Mutated (ATM))

Alternative Name: ATM

Gene ID: 472

OMIM: 607585

Pathways: p53 Signaling, Apoptosis, DNA Damage Repair, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus