Kallikrein 7 antibody (N-Term)

Catalog No. ABIN488082

Product Details anti-Kallikrein 7 Antibody

Target: Kallikrein 7 (KLK7)

Binding Specificity: AA 1-237, N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Kallikrein 7 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: Recognizes Kallikrein-7/KLK7.
Cellular Localization: Secreted.

Cross-Reactivity (Details): Species reactivity (tested):Human.

Purification: Antigen-Affinity Chromatography.

Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 1 and 237 of Human KLK7

Application Details

Application Notes: Western blotting: 1/500-1/3000. Positive Controls: 293TImmunohistochemistry on Formalin-Fixed Paraffin-Embedded Sections.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.7 mg/mL

Buffer: 0.1 M Tris, 0.1 M Glycine, 10 % Glycerol ( pH 7), 0.01 % Thimerosal

Preservative: Thimerosal (Merthiolate)

Precaution of Use: This product contains thimerosal (merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: -20 °C

Storage Comment: Store the antibody undiluted at (in aliquots) at -20 °C.

Target Details for Kallikrein 7

Target: Kallikrein 7 (KLK7)

Alternative Name: KLK7 / Kallikrein-7 (KLK7 Products)

Synonyms: Prss6 antibody, SCCE antibody, PRSS6 antibody, hK7 antibody, kallikrein related-peptidase 7 (chymotryptic, stratum corneum) antibody, kallikrein-related peptidase 7 antibody, kallikrein related peptidase 7 antibody, Klk7 antibody, KLK7 antibody

Background: Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its encoded enzyme is thought to be involved in the proteolysis of intercellular cohesive structures preceding desquamation, which is the shedding of the outermost layer of the epidermis. Alternative splicing of this gene results in two transcript variants encoding the same protein.Synonyms: PRSS6, SCCE, Serine protease 6, Stratum corneum chymotryptic enzyme, hK7

Gene ID: 5650, 9606

UniProt: P49862

Pathways: Complement System