ALDH1A2 antibody (AA 1-110)

Catalog No. ABIN4886449

Product Details anti-ALDH1A2 Antibody

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Binding Specificity: AA 1-110

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ALDH1A2 antibody is un-conjugated

Application: Western Blotting (WB)

Purpose: Rabbit IgG polyclonal antibody for Retinal dehydrogenase 2(ALDH1A2) detection. Tested with WB in Human,Mouse,Rat.

Cross-Reactivity (Details): Predicted Cross Reactivity: human
No cross reactivity with other proteins.
Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.

Characteristics: Rabbit IgG polyclonal antibody for Retinal dehydrogenase 2(ALDH1A2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: aldehyde dehydrogenase 1 family member A2
Protein Name: Retinal dehydrogenase 2

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ALDH1A2 recombinant protein (Position: M1-A110). Human ALDH1A2 shares 95.5% amino acid (aa) sequence identity with both mouse and rat ALDH1A2.

Isotype: IgG

Application Details

Application Notes: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ALDH1A2

Target: ALDH1A2 (Aldehyde Dehydrogenase 1 Family, Member A2 (ALDH1A2))

Alternative Name: ALDH1A2 (ALDH1A2 Products)

Synonyms: Raldh-2 antibody, RALDH(II) antibody, RALDH2 antibody, RALDH2-T antibody, fb50h01 antibody, raldh2 antibody, AV116159 antibody, Aldh1a7 antibody, Raldh1 antibody, Raldh2 antibody, aldehyde dehydrogenase 1 family, member A2 antibody, aldehyde dehydrogenase 1 family member A2 antibody, aldehyde dehydrogenase family 1, subfamily A2 antibody, Aldh1a2 antibody, ALDH1A2 antibody, aldh1a2 antibody

Background: Aldehyde dehydrogenase 1 family, member A2, also known as ALDH1A2 or retinaldehyde dehydrogenase 2 (RALDH2), is an enzyme that in humans is encoded by the ALDH1A2 gene. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

Synonyms: ALDH1A2 | Aldh1a7 | RALDH 2 | RALDH(II) | Raldh1 | RalDH2 | Retinal dehydrogenase 2 | O94788

Gene ID: 8854

UniProt: O94788

Pathways: Retinoic Acid Receptor Signaling Pathway