MUC3B antibody (C-Term)

Catalog No. ABIN4886675

The Rabbit Polyclonal anti-MUC3B antibody is suitable to detect MUC3B in samples from Human. It has been validated for WB.

Quick Overview for MUC3B antibody (C-Term) (ABIN4886675)

Target: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This MUC3B antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-MUC3B Antibody

Binding Specificity: C-Term

Purpose: Anti-MUC3/MUC3A/MUC3B Antibody

Sequence: DLNDNTSQAY RDFNKTFWNQ MQKIFADMQG FTFK

Specificity: No cross reactivity with other proteins.

Cross-Reactivity (Details): No cross-reactivity with other proteins

Characteristics: Anti-MUC3/MUC3A/MUC3B Antibody. Tested in WB applications. This antibody reacts with Human.

Purification: Immunogen affinity purified.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human MUC3.

Isotype: IgG

Application Details

Application Notes: Western blot, 0.1-0.5 μg/mL, Human

Comment:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains antibody formulated with stabilizing components, 0.9 mg NaCl, 0.2 mg Na2HPO4, and 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C,-20 °C

Storage Comment: Store at -20°C for one year from date of receipt. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20°C for six months. Avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for MUC3B

Target: MUC3B (Mucin 3B, Cell Surface Associated (MUC3B))

Alternative Name: MUC3B

Background:

Background: MUC3 consists of two genes, MUC3A and MUC3B, each encoding membrane-bound mucins possessing 2 epidermal growth factor-like domains. The MUC3 gene is mapped to chromosome 7. It was showed that synthetic peptide-mediated upregulation of MUC3 dramatically inhibited adherence of enteropathogenic E. coli or enterohemorrhage E. coli serotype O157:H7 to HT-29 human intestinal epithelial cells. Peptide stimulation altered expression of a number of transcription factors, including upregulation of SP1, CREB1, and CDX2. These transcription factors bound to consensus sites in the MUC3 promoter upon peptide stimulation and likely mediated MUC3 upregulation.

Gene Full Name: Mucin-3B

Molecular Weight: 345 kDa

Gene ID: 4584, 57876

UniProt: Q9H195