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SLC1A3 antibody (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 3) (AA 14-42) Primary Antibody

SLC1A3 Reactivity: Human, Mouse, Rat IHC (p), WB Host: Rabbit Polyclonal unconjugated
Pubmed (1)
Catalog No. ABIN4886724
$280.00
Plus shipping costs $45.00
100 μg
local_shipping Shipping to: United States
Delivery in 4 to 6 Business Days
  • Target
    SLC1A3
    Binding Specificity
    • 23
    • 16
    • 7
    • 6
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 14-42, N-Term
    Reactivity
    • 58
    • 46
    • 23
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 55
    • 14
    • 5
    Rabbit
    Clonality
    • 68
    • 6
    Polyclonal
    Conjugate
    • 37
    • 6
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This SLC1A3 antibody is un-conjugated
    Application
    • 53
    • 36
    • 18
    • 18
    • 13
    • 13
    • 9
    • 9
    • 6
    • 4
    • 2
    • 1
    • 1
    Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
    Purpose
    Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 1(SLC1A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Sequence
    RMERFQQGVR KRTLLAKKKV QNITKEDVK
    Cross-Reactivity (Details)
    No cross reactivity with other proteins.
    Characteristics
    Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 1(SLC1A3) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
    Gene Name: solute carrier family 1 (glial high affinity glutamate transporter), member 3
    Protein Name: Excitatory amino acid transporter 1
    Purification
    Immunogen affinity purified.
    Immunogen
    A synthetic peptide corresponding to a sequence at the N-terminus of human EAAT1 (14-42aa RMERFQQGVRKRTLLAKKKVQNITKEDVK), different from the related mouse sequence by three amino acids, and identical to the related rat sequence.
    Isotype
    IgG
  • Application Notes
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Comment

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
  • Ding, Zhang, Liu, Zhang, Ma, Bruce, Zhang: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." in: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, 2014 (PubMed).

  • Target
    SLC1A3
    Alternative Name
    SLC1A3 (SLC1A3 Antibody Abstract)
    Synonyms
    AF001784, CG3747, Dglt-1, Dglut-1, Dmel\\CG3747, EAAT, EAAT1, dEAAT, dEAAT1, dEaat1, slc1a3, wu:fb98e05, wu:fd50b05, zgc:56661, zgc:77768, SLC1A3, GLAST, GluT-1, EA6, GLAST1, AI504299, B430115D02Rik, Eaat1, GLAST-1, GLU-T, Gmt1, MGluT1, Excitatory amino acid transporter 1, solute carrier family 1 member 3, excitatory amino acid transporter 1, solute carrier family 1 (glial high affinity glutamate transporter), member 3a, solute carrier family 1 (glial high affinity glutamate transporter), member 3, Eaat1, SLC1A3, PTRG_00379, Tsp_02392, slc1a3a, Slc1a3
    Background
    Solute carrier family 1 (glial high-affinity glutamate transporter), member 3, also known as SLC1A3, EAAT1 or GLAST, is a protein that in humans is encoded by the SLC1A3 gene. This gene is a member of high affinity glutamate transporter family. It is mapped to chromosome 5p13.2 by fluorescence in situ hybridization (FISH). And this gene transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Furthermore, this gene acts as a symport by cotransporting sodium.

    Synonyms: EA6 | EAA1 | EAAT 1 | EAAT1 | EAAT1 | GLAST | GLAST1 | Glast | GLAST-1 | SLC1A3 | P43003
    Gene ID
    6507
    UniProt
    P43003
    Pathways
    Sensory Perception of Sound, Synaptic Membrane, Dicarboxylic Acid Transport
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