Huntingtin antibody (N-Term)
Quick Overview for Huntingtin antibody (N-Term) (ABIN4889208)
Target
See all Huntingtin (HTT) AntibodiesReactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- N-Term
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Specificity
- Reacts with the human Huntingtin protein
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Cross-Reactivity
- Mouse (Murine), Rat (Rattus)
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Cross-Reactivity (Details)
- Cross react with mouse and rat protein due to sequence homology.
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Purification
- Purified (protein A)
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Immunogen
- synthetic peptide derived from N terminal part of human Huntingtin
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Application Notes
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Working dilution: Optimal dilutions should be determined by the end user.
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Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Must be reconstituted in distilled water.
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Concentration
- 1 mg/mL
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Buffer
- Tris 0,1M, glycine 0,1M, sucrose 2 %
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Storage
- 4 °C/-20 °C
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Storage Comment
- Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
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Expiry Date
- 24 months
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- Huntingtin (HTT)
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Alternative Name
- Huntingtin
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Background
- Defects in HTT are the cause of Huntington disease (HD). HD is an autosomal dominant neurodegenerative disorder characterized by involuntary movements (chorea), general motor impairment, psychiatric disorders and dementia.
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UniProt
- P42858
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Pathways
- PI3K-Akt Signaling, Hormone Transport, Transition Metal Ion Homeostasis, Tube Formation, Protein targeting to Nucleus, Dicarboxylic Acid Transport
Target
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