Merlin antibody (C-Term, pThr582)

Catalog No. ABIN4889342

The Rabbit Polyclonal anti-Merlin antibody is suitable to detect Merlin in samples from Human and Mouse. It has been validated for WB, ELISA and IF.

Quick Overview for Merlin antibody (C-Term, pThr582) (ABIN4889342)

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Merlin antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Product Details anti-Merlin Antibody

Binding Specificity: C-Term, pThr582

Specificity: Reacts with 70 kDa Merlin pT582 from human and mouse

Cross-Reactivity (Details): Cross react with isoform 9 of Merlin (19 kDa)

Purification: Purified (protein A)

Immunogen: Synthetic peptide derived from C terminal part of human Merlin containing a phospho Thréonine 582 .

Application Details

Application Notes:

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
WB1:200-1:2000 IF1:200 - 1:2000

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Must be reconstituted in distilled water.

Concentration: 1 mg/mL

Buffer: Tris 0,1M, glycine 0,1M, sucrose 2 %

Storage: 4 °C/-20 °C

Storage Comment: Lyophilized powder stable for a minimum of 2 years at -20°C. Store reconstituted antibodies at +4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.

Expiry Date: 24 months

Target Details for Merlin

Target: Merlin (NF2) (Neurofibromin 2 (NF2))

Alternative Name: Merlin

Background: Involved in a branch of the regulation of the Hippo pathway. Suppresses cell proliferation and tumorigenesis.

Gene ID: 4771

UniProt: P35240

Pathways: Cell-Cell Junction Organization