Prohibitin 2 antibody (PHB2) (C-Term)

Details for Product anti-PHB2 Antibody No. ABIN4889443, Supplier: Log in to see
Antigen
  • bcap37
  • zgc:73150
  • wu:fc28c08
  • PHB2
  • phb2
  • ATPHB2
  • F21M11.21
  • F21M11_21
  • prohibitin 2
  • DKFZp469N1310
  • BAP
  • BCAP37
  • Bap37
  • PNAS-141
  • REA
  • p22
  • bap37
  • prohibitin2
  • xphb2
  • AU044498
  • Bcap37
  • Bap
  • Bap-37
  • Bcap27
  • prohibitin 2a
  • prohibitin 2
  • prohibitin 2 S homeolog
  • phb2a
  • PHB2
  • phb2
  • phb2.S
  • Phb2
Alternatives
anti-Human Prohibitin 2 antibody for Immunocytochemistry
Epitope
C-Term
21
17
10
7
7
6
4
3
3
3
3
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
133
65
43
12
9
8
7
5
3
2
2
2
2
2
1
1
1
Host
Rabbit
131
3
3
Clonality
Polyclonal
Conjugate
This Prohibitin 2 antibody is un-conjugated
6
6
5
5
5
4
1
1
1
1
1
1
1
1
1
1
1
1
Application
ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Western Blotting (WB)
110
55
48
34
17
13
13
12
5
4
3
3
2
2
1
1
Options
Supplier
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Immunogen Synthetic peptide of derived from C terminal part of human Prohibitin-2.
Specificity Reacts with MBD3 from human, mouse, rat and other species (due to sequence homology)
Purification Purified (protein A)
Plasmids, Primers & others Plasmids, Primers & others Prohibitin 2 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name Prohibitin-2 (PHB2 Antibody Abstract)
Background Acts as a mediator of transcriptional repression by nuclear hormone receptors via recruitment of histone deacetylases. Functions as an estrogen receptor (ER)-selective coregulator that potentiates the inhibitory activities of antiestrogens and represses the activity of estrogens. Competes with NCOA1 for modulation of ER transcriptional activity. Probably involved in regulating mitochondrial respiration activity and in aging.
Gene ID 11331
UniProt Q99623
Pathways Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling
Application Notes

Working dilution: Optimal dilutions should be determined by the end user.
The following are guidelines only:
- WB : 1/500 to 1/2000 - ICC, IF: 1/200 to 1/1000

Restrictions For Research Use only
Format Lyophilized
Reconstitution Must be reconstituted in distilled water.
Concentration 1 mg/mL
Buffer Tris 0,1M, glycine 0,1M
Storage 4 °C/-20 °C
Storage Comment Short term storage at+4°C. For extended periods store in aliquots at -20°C. Antibodies are guaranteed for 6 month from date of receipt.
Expiry Date 6 months
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