NF-kB p65 antibody (C-Term)

Catalog No. ABIN4889656

The Rabbit Polyclonal anti-NF-kB p65 antibody has been validated for WB and ChIP. It is suitable to detect NF-kB p65 in samples from Human. There are 3+ publications available.

Quick Overview for NF-kB p65 antibody (C-Term) (ABIN4889656)

Target: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NF-kB p65 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Product Details anti-NF-kB p65 Antibody

Binding Specificity: C-Term

Purification: None

Immunogen: This NFkB p65 antibody was raised against a peptide immunogen corresponding to the C-terminal of human p65.

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -20 °C

Storage Comment: Antibodies in solution can be stored at -20 °C for 2 years.

Expiry Date: 6 months

References for anti-NF-kB p65 antibody (ABIN4889656)

Diermeier, Kolovos, Heizinger, Schwartz, Georgomanolis, Zirkel, Wedemann, Grosveld, Knoch, Merkl, Cook, Längst, Papantonis: "TNF? signalling primes chromatin for NF-?B binding and induces rapid and widespread nucleosome repositioning." in: Genome biology, Vol. 15, Issue 12, pp. 536, (2015) (PubMed).

Raaz, Schellinger, Chernogubova, Warnecke, Kayama, Penov, Hennigs, Salomons, Eken, Emrich, Zheng, Adam, Jagger, Nakagami, Toh, Toyama, Deng, Buerke, Maegdefessel, Hasenfuß, Spin, Tsao: "Transcription Factor Runx2 Promotes Aortic Fibrosis and Stiffness in Type 2 Diabetes Mellitus." in: Circulation research, Vol. 117, Issue 6, pp. 513-24, (2015) (PubMed).

Anderson, Rahmutula, Gardner: "Tumor necrosis factor-alpha inhibits endothelial nitric-oxide synthase gene promoter activity in bovine aortic endothelial cells." in: The Journal of biological chemistry, Vol. 279, Issue 2, pp. 963-9, (2004) (PubMed).

Target Details for NF-kB p65

Target: NF-kB p65 (NFkBP65) (Nuclear Factor-kB p65 (NFkBP65))

Alternative Name: NFkappaB p65

Molecular Weight: 65 kDa

Gene ID: 5970

Pathways: NF-kappaB Signaling, RTK Signaling, TCR Signaling, TLR Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Toll-Like Receptors Cascades, S100 Proteins